Guan Lab

Department of Computational Medicine & Bioinformatics
Found 12 results
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Menden MP, Wang D, Mason M, Szalai B, Bulusu KC, Guan Y, et al.  2019.  Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen. Nature Communications. (10, Article number: 2674 (2019))
Siddiqui O, Zhang H, Guan Y, Omenn G.  2018.  Chromosome 17 Missing Proteins: Recent Progress and Future Directions as part of the Next-50MP Challenge. Journal of Proteome Research. doi: 10.1021/acs.jproteome.8b00442. [Epub ahead of print]
Al'Aref SJ, Anchouche K, Singh G, Slomka PJ, Kolli KK, Kumar A, others, Guan Y, Min JK.  2018.  Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging.. Eur Heart J. Jul 27. doi: 10.1093/eurheartj/ehy404.
Gönen M, Weir BA, Cowley GS, Vazquez F, Guan Y, Jaiswal A, Karasuyama M, Uzunangelov V, Wang T, Tsherniak A.  2017.  A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines.. Cell Syst.. Nov 22;5(5):485-497.e3. doi: 10.1016/j.cels.2017.09.004. Epub 2017 Oct 4.
Ramani B, Panwar B, Moore LR, Wang B, Huang R, Guan Y, Paulson HL.  2017.  Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.. Hum Mol Genet.. (Sep 1;26(17):3362-3374, doi:10.1093/hmg/ddx224)
Huang Z, Zhang H, Boss J, Goutman SA, Mukherjee B, Dinov ID, Guan Y.  2017.  Complete hazard ranking to analyze right-censored data: An ALS survival study.. PLoS Comput Biol. Dec 18;13(12):e1005887. doi: 10.1371/journal.pcbi.1005887.
Zhu F, Panwar B, Dodge HH, Li H, Hampstead BM, Albin RL, Paulson HL, Guan Y.  2016.  COMPASS: A computational model to predict changes in MMSE scores 24-months after initial assessment of Alzheimer's disease.. Sci Rep. 6:34567.
Sieberts SK, Zhu F, García-García J, others, Eksi R, others, Li H, others, Guan Y, Mangravite LM.  2016.  Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.. Nat Commun. 7:12460.
Allen GI, Amoroso N, Anghel C, others, Guan Y, others, Zhu F, Zhu H, Zhu S.  2016.  Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.. Alzheimers Dement.
Guan Y, Dunham MJ, Troyanskaya OG, Caudy AA.  2013.  Comparative gene expression between two yeast species.. BMC Genomics. 14:33.
Peña-Castillo L, Tasan M, Myers CL, Lee H, Joshi T, Zhang C, Guan Y, Leone M, Pagnani A, Kim WKyu et al..  2008.  A critical assessment of Mus musculus gene function prediction using integrated genomic evidence.. Genome Biol. 9 Suppl 1:S2.